History Highly pathogenic avian influenza viruses of the H5N1 subtype continue to cross the species barrier to infect humans and cause severe disease. H5N1 virus whereas no such differences were observed with the less virulent A/PR/8/34 (H1N1) virus. H5N1 infected TM mice displayed diminished cytokine production in lung tissue and a quantifiable decline of macrophages… Continue reading History Highly pathogenic avian influenza viruses of the H5N1 subtype continue