Activation of is an important mechanism in apoptosis. localization in mitochondria and apoptosis. Together the data indicate that the presence of p53 in mitochondria plays an important role in stress-induced apoptosis and suggest that NPM may protect cells from apoptosis by reducing the mitochondrial level of p53. The tumor suppressor functions of are mediated by… Continue reading Activation of is an important mechanism in apoptosis. localization in mitochondria